Sepsis is a life-threatening medical condition that kills nearly 350,000 Americans every year.

Sepsis is the body’s extreme response to an infection that can lead to organ failure or even death. While many people recover from sepsis, some survivors may experience life-changing complications.

While bacterial infections are the most common cause, sepsis can result from fungal infections, parasites or viral infections.

“A respiratory illness, urinary tract infection or even an infected wound on your skin can lead to sepsis,” said Peter Schubel, MD, emergency medicine physician and medical director with Endeavor Health.

Sepsis can strike anyone regardless of how minor or major an infection may be. Those at highest risk typically include:

  • People with compromised immune systems or chronic illnesses like cancer, AIDS and diabetes
  • Infants and young children
  • Those over age 65
  • Pregnant people

There are some warning signs of sepsis that everyone should know. The Sepsis Alliance uses the acronym TIME to list them:

T: Temperature higher or lower. People with sepsis might also have clammy or sweaty skin, shivers, fever or feeling very cold.
I: Infection. Sometimes infections have no symptoms. Look for signs of infection or think about whether you have been exposed to an infection through a recent surgery, a cut in your skin or an interaction with someone who was ill. 
M: Mental decline. Sepsis can cause mental symptoms, such as confusion, disorientation or severe sleepiness. 
E: Extremely ill. Sepsis can cause people to feel that their illness was the worst they’ve felt – the worst pain or feeling like they might die.

If you think you or someone else may have sepsis, it’s important to go to an emergency room right away and for evaluation. Sepsis is treated with antibiotics, though patients may also receive oxygen and intravenous fluids.

“There are things you can do to protect yourself from sepsis,” Dr. Schubel said. “Getting vaccinated against flu, pneumonia and other infections is an important step. Clean and protect any scrapes or wounds you may have. And make bathing and handwashing a regular part of your daily routine.”

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