About Stuart Sprague, DO

Stuart Sprague, DO, a nephrologist at Endeavor Health, brings decades of clinical experience and research to the care of patients with kidney disease. His work spans rare diseases, mineral metabolism and complex diagnostic challenges. Dr. Sprague is known for a patient-centered approach, especially for those who don’t fit typical treatment algorithms, and he continues to explore innovations in dialysis and artificial kidney development.

My endeavor

My endeavor is to approach every patient as an individual, try to deal with the problem they have, and come to a resolution together to improve their quality of life.

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Care philosophy

Patient care must be individualized. I don’t believe in forcing patients into algorithms that may not fit. I address each patient’s condition in the context of their life, other health issues and overall wellbeing, using logical, physiology-based treatment to create the best plan for them.

Overview

  • Languages Yiddish
  • Gender Male

Conditions treated (13)

  • Glomerular diseases
  • Osteoporosis
  • Mineral disorders
  • Hyperparathyroidism
  • Polycystic kidney disease (PKD)
  • Acute kidney injury (AKI)
  • Chronic kidney disease
  • Electrolyte disorders
  • End stage renal disease
  • Kidney stone disease
  • Metabolic bone disorders
  • Nephrotic syndrome
  • Transplant kidney disease

Procedures performed (4)

  • Dialysis
  • Bone biopsy
  • Home-based dialysis
  • Kidney biopsy

Medical School
  • 1982
    Michigan State University
Residencies
  • 1986
    Internal Medicine
    Rush-Presbyterian-St Luke's Medical Center
Fellowships
  • 1989
    Nephrology
    University of Chicago
Board certifications
  • 1986
    Internal Medicine
    American Board of Internal Medicine
  • 1988
    Nephrology
    American Board of Internal Medicine
Academic title
  •  
    Clinical Professor, The University of Chicago Pritzker School of Medicine

Reviews (95)
July 25, 2026
He is very patient
July 23, 2026
Sad to see him retire
No rating
July 11, 2026
Dr. Sprague was great. He had thoroughly reviewed my file, and was well prepared for my visit. When I described the recent death of my spouse, he was appropriately sympathetic and expressed the same [...] sentiment that I have been feeling. He seems like a real human with whom I would like to have an adult beverage.
July 2, 2026
I have been under Dr. Sprague's care for about 3-4 years and have always found him to be caring, thorough, professional and relaxing, which put me at ease through my diagnosis and remission of Sarcoid. He and [...] worked well to coordinate my care...and they have released me from further care.
July 1, 2026
Easy to talk to, puts you immediately at ease, very professional and to the point
June 23, 2026
No,delays
June 16, 2026
Dr. Sprague is going to be missed. He's the real deal
June 13, 2026
Excellent
June 12, 2026
Dr. Sprague is a wonderful physician and a senior nephrology physician.
May 23, 2026
Dr. Sprague is an excellent physician. I have found him and his staff to be very responsive and supportive -- they have helped relieve my anxiety about CKD and have given me clear instructions for routines I must maintain to help keep my disease from progressing.
May 16, 2026
Dr. Sprague is so attentive and completely focused on the patient. He had reviewed my chart beforehand and was extremely thorough in his exam and assessment.
May 10, 2026
Dr. Sprague has been an excellent clinician understanding and discussing my problems and advising me on my care.
May 1, 2026
The best!
April 30, 2026
Dr. Sprague is a wonderful nephrologist. I will miss seeing him on future visits.
April 25, 2026
Dr Sprague is an excellent physician!
April 22, 2026
Very thorough and not in a hurry. Eager to answer questions clearly.
April 17, 2026
Sprague is outstanding and he will be missed when he retires
April 16, 2026
Everyone from Dr. Sprague to the nurses, receptionist were extremely professional Knowledgeable. I was very pleased with the care I received from them
April 16, 2026
As always, pleasant and helpful. Patient feels listened and responded to with care and thought.
March 30, 2026
Dr. Sprague, is a caring provider. We are grateful to him for his treatment of Barbara these last few years and will miss him dearly. We wish him good luck in his retirement and hope he has continued good health as he embarks on this next chapter of his life.
March 25, 2026
My care provider is a excellent doctor.
March 25, 2026
Feel sad knowing he is retiring. Thank you for your care.
March 21, 2026
Holistic, caring, connects the dots
March 20, 2026
Dr. Sprague does a careful physical examination, as well as being an expert on interpreting the laboratory tests
March 19, 2026
Love Dr Sprague. He is thorough and smart
March 13, 2026
Good care provider.
March 11, 2026
Dr. SPRAGUE is a very knowledgeable and proficient Nephrologist! His bedside manner is without peer! His care for me over the years has been wonderful. I wish him all the best in his upcoming retirement! [...]
March 9, 2026
Wonderful doctor
February 14, 2026
Outstanding service and professionalism
February 11, 2026
He is excellent.
February 10, 2026
I will miss you, Dr. Sprague
February 8, 2026
Thorough, conversational, integrated other treatments into analysis
February 6, 2026
He is caring, professional, communities, and works with my other team of doctors.
February 5, 2026
Dt Sprague has vast experience and knowledge in the several conditions I have. Rare to find. Great care and treatment. Pleasant, attentive.
February 5, 2026
He listens
January 31, 2026
Dr Sprague is amazing, kind, and compassionate
January 26, 2026
Took the time to review my record and showed a genuine concern for my wellbeing
January 25, 2026
Dr Sprague will be dearly missed. Wonderful Physician and human. Thank you for assisting me in my health journey Dr Sprague.
January 24, 2026
Dr. Sprague is retiring. He's provided excellent care and will be greatly missed.
January 14, 2026
Extremely thorough. A good listener. Communicated with me clearly.
January 14, 2026
Excellent
January 10, 2026
Excellent. After years of trying to get my Litholink 24 Hr Urine Panel results to a level of acceptable kidney stone supersaturation risk control, we are one modification and test result away from complete success.
January 10, 2026
Very good thanks
December 23, 2025
Very good
December 18, 2025
I will miss Dr Sprague when he retires. I am concerned I will have someone who is as thorough and caring.
December 18, 2025
He is an expert in his field & rare combination of extreme decency with his bedside mannor
December 4, 2025
Dr, Sprague is very considerate, observant and thorough.
December 3, 2025
Dr. Sprague is a very special doctor. I am always treated kindly and am not patronized. I have had many serious ailments and he is an exceptional physician. But that is well known.
November 29, 2025
I am grateful to have been a patient of Dr Sprague, now that he is retiring. He has given me good care and advise that has helped my condition.
November 27, 2025
Very knowledgeable and kind
November 17, 2025
Dr. Sprague is outstanding. His professionalism, expertise and compassion for his patients is deeply appreciated. I look forward to my annual check ups.
November 14, 2025
Dr Sprague is outstanding re knowledge, care, rapport and other attributes
November 14, 2025
I always receive prompt replies to messages I send online, never wait more than a few minutes for my appointment. Excellent department.
November 2, 2025
My care provider is very knowledgeable and easy to speak with and ask questions
October 31, 2025
Dr Sprague is wonderful
October 31, 2025
Dr. Sprague was excellent - through, clear in his explanations, provides excellent follow-up care.
October 29, 2025
Dr. Sprague is excellent. He is very knowledgeable and provides excellent care
October 19, 2025
Everything went well. There was no delay. I felt cared for by everyone I spoke with.
October 3, 2025
Dr Sprague is a thorough, smart and wonderful doctor/person. He asks all the right questions and gives good feedback.
September 16, 2025
Dr. Sprague is a caring, informed , intelligent and excellent doctor. He advocates for his patients and does not give up on them no matter how difficult the diagnosis and treatment plan is. I feel so supported in his care.
September 14, 2025
Attentive, thorough, professional, answered all my question, pleasant, very understanding and received good recommendations
September 11, 2025
He is a wonderful doctor.
September 9, 2025
Dr. Sprague was kind, thorough, took his time, and very knowledgeable. He explained things well and put my mind at eae.
September 3, 2025
I would highly recommend Dr Sprague.
August 30, 2025
Explained everything thoroughly
August 30, 2025
Dr Sprague is very thorough. He reviews test results ahead of time and replies on Northshore Connect. I'll miss his care when he retires.
August 13, 2025
Excellent doctor and staff
August 12, 2025
Dr Sprague always takes the time to go over test results and answer all questions.
August 1, 2025
It all went well.
July 31, 2025
Dr Sprague is incredibly knowledgeable about calcium levels which is important to me since I have no parathyroid gland
July 30, 2025
Dr sprague superb in all respects
July 30, 2025
Dr. Sprague is very knowledgeable, caring, an outstanding dr
July 29, 2025
Dr Sprague has given me excellent medical care for some difficult situations
July 27, 2025
Dr. Sprague is outstanding! Very thorough, highly professional. I trust him impicitly.
July 24, 2025
He is warm and brilliant
No rating
July 24, 2025
Stuart is one of the best. He helped me to get and stay better. He is kind. Thoughtful. And will be missed.
July 21, 2025
I love Dr Sprague, kind compassionate smart supportive and authentic. A team player and a very good Doctor!!
July 17, 2025
Excellent. Very special and helpful. I did refer him to a friend of mine who has similar issues.
July 8, 2025
Very thorough
July 6, 2025
We had a lot to review and Dr S tookHis time to explain everything to me.
July 4, 2025
Dr Sprague is wonderful. I'm been seeing him for almost 20 years and I don't know where I would be without his care.
July 2, 2025
Nothing just keep doing what you've been doing as far as training goes, your staff provides great customer service from start to finish.
June 13, 2025
Dr Sprague is the finest Dr in his field
June 13, 2025
Dr Sprague was easy to talk with. He took time to listen to my concerns.
June 11, 2025
No delays
June 10, 2025
Dr. Sprague always listens Intently to me as the patient. He is very thorough in his questioning of me. I am very pleased with the care I receive from him and the office.
June 4, 2025
Wonderful
May 30, 2025
I have been very fortunate to be in the medical care of Dr. Sprague. He has addressed my medical issues thoroughly and successfully.
May 2, 2025
I felt very taken care of and attended too by Dr Sprague and his office staff.
April 27, 2025
Dr. Sprague is very thorough and professional.
April 16, 2025
I am confident in Dr. Spprague's ability to manage by kidney disease.
April 8, 2025
Excellent provider.
April 2, 2025
Excellent. Dr Sprague is the best doctor I deal with.
April 1, 2025
The best! The kindest! Doesn't rush through appointment. Answers questions.
April 1, 2025
Excellent!

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