Endeavor Health’s Research Institute fuels groundbreaking discoveries and innovation, driving advancements that save and improve lives.

We conduct transformative research across multiple disciplines — from oncology and neurology, to orthopaedics, cardiovascular care and more. Our goal is to better understand health conditions and quickly turn breakthrough science into diagnostics, treatments and therapies. 

With expertise in personalized medicine, advanced informatics and a vast portfolio of clinical trials, we proudly stand among the nation’s leading independent research hospital systems.

Our research focus areas

Cardiac surgeon explaining a heart procedure during a consultation setting
Cardiovascular Institute
Orthopaedics hand surgeons performing a surgery
Orthopaedics Institute
A woman with a radiant smile, wearing a headscarf, is ringing a ceremonial bell in a hospital setting, signifying a milestone in her cancer treatment. She is joyously surrounded by healthcare staff clapping and sharing in the celebration of this significant moment in her journey to recovery.
Cancer Institute
Neuro surgeon greeting a patient before an operation
Neurosciences Institute
Woman patient looking at clipboard with her doctor
Women’s Health
A woman hugging her mother while she is sitting in the kitchen
Personalized Medicine
Female doctor looking into a microscope
Advancing medicine through clinical trials

With more than 550 active clinical trials, Endeavor Health is pushing the boundaries of medicine with innovative surgeries, therapies and approaches in cancer, neurology, cardiovascular health, pediatrics, gynecology and more. We’re also home to pioneering programs in advanced imaging and medical genetics, including the largest advanced primary care genomics program in the nation.

Through seamless collaboration with departmental leaders, physicians and staff, our Clinical Trials Center is growing as a nationally recognized hub of excellence — delivering cutting-edge research that gives patients access to tomorrow’s treatments today.

Learn more about Endeavor Health clinical trials

Trailblazing investigators

We attract the brightest minds — nearly 300 world-class principal investigators leading a broad range of studies, from investigator-initiated projects to high-impact, industry-sponsored clinical trials.

Fueled by millions in external funding, including prestigious NIH grants and generous philanthropy, our research covers everything from fundamental discovery to rapid clinical translation. As leaders in multi-center studies, our investigators don’t just contribute — they steer research efforts on the world stage.

We also have dozens of clinicians who serve as endowed research chairs – the highest academic honor in medicine. These chairs represent some of the brightest, most influential minds in their fields, all working to further research that will shape the future of medicine.

Learn more about our chairs

Contact our Research Institute

To learn more or get involved call (224) 364-7100 or email research [at] northshore.org (research[at]northshore[dot]org).