Choosing to participate in a clinical trial is a big decision — and where you choose to participate matters. At Endeavor Health, our clinical trials are led by experienced, trusted physicians dedicated to advancing cardiovascular care and improving patient outcomes. We’re committed to providing a safe, transparent and supportive environment for every participant, making sure you’re informed and cared for throughout your journey.

Our research team conducts over 550 active clinical trials across Chicagoland, tackling some of healthcare’s greatest challenges right in your community. From cardiovascular disease and heart failure to high blood pressure and coronary heart disease, our trials span a wide range of heart health conditions, offering patients unique access to innovative treatments and groundbreaking therapies. All clinical trials performed at Endeavor Health have been vetted by the FDA.
By choosing Endeavor Health, you’re not only gaining access to advanced care — you’re also joining a community of researchers and patients working together to shape the future of heart health. We believe that every participant makes a difference, and we’re in it together.
What is a clinical trial?
A clinical trial is a research study where volunteers help test and evaluate new treatments, interventions or lifestyle strategies for heart health. From medications and devices, to targeted lifestyle changes like new diets or exercise plans, trials explore innovative ways to improve health outcomes.
- Phase I: Focuses on safety, involving 20-100 participants to determine ideal dosage and identify any side effects.<
- Phase II: Tests effectiveness with 100-300 participants, while continuing to monitor safety.
- Phase III: Involves 1,000-3,000 participants to confirm effectiveness, compare with existing treatments, and gather comprehensive safety data.
- Phase IV: Occurs after FDA approval, tracking the treatment's safety, benefits and any long-term effects in the general population.
For many, it’s an opportunity to access the latest in heart treatments — therapies that aren’t yet available to the public. For others, it’s a way to make a meaningful contribution to science, knowing that their participation may help future generations lead healthier lives.
Whether you’re looking for new treatment options or simply want to support research, every participant plays a vital role in advancing heart care.
- Access to new treatments: Experience innovative cardiovascular therapies that may provide benefits beyond standard options.
- Support heart research: Your involvement generates data that could shape the future of heart disease management and prevention.
- Making a difference: By participating, you’re helping doctors and researchers gain insights that can improve outcomes for patients worldwide.
- Prescreening: Researchers will discuss the trial with you, answer any questions and collect preliminary health information to determine if the trial is a good match.
- Informed consent: If you qualify, you’ll go over a detailed consent form that outlines the trial’s purpose, procedures and any potential risks and benefits.
- Screening visit: Once you’ve provided consent, further testing — such as blood samples or health assessments — may be conducted to confirm your eligibility.
- Enrollment and participation: After enrolling, you’ll follow a structured schedule for the trial, with regular check-ins and assessments. Remember, participation is voluntary, and you can withdraw at any time.
- Completion and results: Once the trial concludes, researchers analyze the data. In some cases, you may be informed about results that directly impact your health.

Who can join a clinical trial? Eligibility depends on several factors, including your health history, the type of cardiovascular disease you have and the specific goals of the trial. Common criteria include your age, heart disease type, history of cardiovascular events, blood pressure and other health indicators. Our team will walk you through the prescreening process to see if there’s a trial that aligns with your needs.
Clinical trials lay the foundation for tomorrow’s heart care. They’re essential to developing new treatments for heart failure, understanding how to manage blood pressure and finding preventive approaches for coronary heart disease. Every participant is part of something bigger — helping gather the data that can lead to better health outcomes for heart patients around the world.

Make an appointment
Are you ready to be a part of the future of cardiovascular care? Schedule an appointment with our research team to learn more about clinical trials and discover how you can contribute to a healthier tomorrow.

At Endeavor Health Cardiovascular Institute, your heart health is our mission. With advanced technologies, compassionate care and a dedicated team of specialists, we’re here to help you on every step of your heart health journey.

