Comprehensive care for uterine cancer

Personalized, expert care for uterine cancer — delivered with compassion, innovation and the latest advancements in treatment.

Understanding uterine cancer

Uterine cancer begins in the lining of the uterus and is one of the most common gynecological cancers, especially among women over 40. While the exact cause is unknown, understanding the risk factors can help detect cancer at its earliest stages:

  • Family history of uterine or colorectal cancer
  • Obesity or high body fat
  • Hormone imbalance (especially increased estrogen)
  • Early onset of menstruation or late menopause
  • Diabetes or high blood pressure
  • History of endometrial hyperplasia
  • Lynch syndrome or other genetic predispositions

If you have any of these risk factors, it’s important to speak with a physician about screenings. Early detection can significantly improve treatment outcomes.

Recognizing the signs of uterine cancer

Uterine cancer can present noticeable symptoms from the beginning. If any of these symptoms are persistent, speak with your doctor right away.

Common symptoms include:

  • Abnormal vaginal bleeding (after menopause or between periods)
  • Pelvic pain or pressure
  • Pain during intercourse
  • Unusual vaginal discharge
  • Challenging or painful urination

These symptoms do not always indicate cancer, but should always be assessed by your healthcare professional.

Uterine cancer diagnosis and staging

Our gynecological cancer specialists use a combination of tests to diagnose and stage uterine cancer, including:

A routine pelvic exam allows your doctor to identify any abnormal masses or changes in the size or shape of your uterus. A pelvic exam remains a primary source of information and can point to the need for any further testing.

This imaging test uses sound waves to create a picture of the uterus. It involves inserting a small probe into the vagina to provide a close-up image of any irregularities, including within the uterus lining.

The most definitive way to diagnose cancer is through a biopsy procedure. Doctors collect a small tissue sample from the uterus and use it to confirm the presence of cancer cells.

If a mass is identified within the uterus, imaging tests can offer more detailed information. These scans can help physicians understand the size, precise location and whether cancer has spread to other parts of the anatomy, including lymph nodes or other organs.

Surgical staging involves minimally invasive surgery to help physicians determine the extent of the cancer and the stage. This allows your care team to make well-informed treatment decisions.

Advanced treatment options

Endeavor Health is with you every step of the way throughout your uterine cancer journey. We offer a variety of options for your personalized treatment plan:

Radiation therapy is a frequently used modality to complement surgery for uterine cancer. This may be external beam (IMRT) or brachytherapy to help prevent a recurrence at the vaginal cuff.

Surgery is often the first step in treatment. Depending on the stage of cancer and your needs, options may include:

  • Hysterectomy (removal of the uterus)
  • Salpingo-oophorectomy (removal of the fallopian tubes and ovaries)
  • Minimally invasive or robotic-assisted surgery for faster recovery

Chemotherapy is a standard treatment that may be administered to destroy cancer cells and reduce recurrence. Targeted therapies are also available, which focus on the specific genetic makeup of cancer cells, leading to more precise and often more effective treatment, as well as fewer side effects.

Care team

You’ll be supported by a team of board-certified gynecologic oncologists, radiation oncologists, surgical specialists and nurse navigators. This team-based, compassionate approach ensures personalized care at every stage of your health journey.

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Uterine cancer FAQs

Abnormal bleeding is the most common early sign, especially postmenopausal bleeding or bleeding between periods. Pelvic pain, unusual discharge or pain during intercourse, may also occur. If you notice any of these signs, promptly consult your physician.

Treatment options include surgery, chemotherapy, hormone therapy, radiation and targeted therapy. Your doctor will personalize your care plan based on your diagnosis and needs.

In some cases, yes. Genetic conditions like Lynch syndrome may increase the risk. Ask about genetic testing and counseling if you have a family history of cancer.

Survival rates vary by stage at diagnosis. Early detection is associated with higher survival rates. Talk to your doctor about your personal risk factors.

Diagnosis typically involves a pelvic exam, transvaginal ultrasound and endometrial biopsy. Imaging or surgical staging may also be recommended.

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Clinical trials & emerging therapies

Endeavor Health participates in cutting-edge clinical trials to give you every chance at the best outcome. Our specialists can determine your eligibility and guide you through this process.

Learn more about clinical trials

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Make an appointment

Early detection saves lives. Schedule a consultation with one of our uterine cancer specialists today. No matter the stage of the journey — expertise and support matters.

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The Endeavor Health Cancer Institute provides expert, compassionate care for uterine cancer — from prevention to survivorship — right here in your community.

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